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| Description: X-trant is used in the palliative treatment of metastatic/progressive carcinoma of prostate, and ensures complete hormonal as well as cytotoxic control. While ensuring reduction in the intensity of pain, and absence of hepatic and renal toxicity, X-trant is a unique anti-tumor agent and its usage would improve performance status of patients suffering from prostate cancer. The medicine is also useful in patients with limited bone marrow reserve. X-trant has a dual mode of action. Structurally, X-trant (estramustine) would be a phosphorylated combination of estradiol and mechlorethamine (nitrogen mustard). The intact molecule acts as an antimitotic agent. It binds to a protein present in the tumor tissue which results in an accumulation of the drug at the target site. NATCO's X-trant ensures not only availability of the drug, but also at an affordable price. |
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